Tag Archives: HIV

Gene editing could help eliminate HIV

Around five years ago, when the gene editing technology CRISPR was still new, Kamel Khalili started work on ways to use the system to treat and cure HIV. Khalili, director of the Comprehensive NeuroAIDS Center at the Lewis Katz School of Medicine at Temple University, showed then that CRISPR could effectively clear HIV in both cells and in animals.

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For the Second Time, Doctors Say They’ve Cleared an HIV Infection Using Stem Cells

Doctors in London, UK have seemingly accomplished a momentous feat in HIV treatment. They claim to have used a stem cell transplant to successfully clear any traces of the virus in their HIV-positive male patient. It’s the second time such a procedure has appeared to permanently treat the lifelong infection, though the doctors caution it’s not a confirmed cure just yet. Continue reading For the Second Time, Doctors Say They’ve Cleared an HIV Infection Using Stem Cells

Why Has Science Only Cured One Person of HIV?

In 2007, a young American man living in Berlin became a marvel of modern medicine when, 12 years after he was diagnosed with HIV, the virus suddenly disappeared from his body. Timothy Ray Brown had been diagnosed with leukemia and received a stem cell transplant treat it. His stem cell donor, it turned out, had a rare genetic mutation known as CCR5-delta 32 that gave Brown resistance to HIV infection. Brown became known as “the Berlin patient.” Ten years later, he is still the only person to have ever been cured of HIV.

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People are apparently injecting themselves with other people’s blood to get high now?

Last summer, police in Bucks County, Pennsylvania picked up a man carrying an unmarked vial of red liquid. During questioning, the 33-year-old explained that the vial contained human blood and fentanyl, a painkiller 50 to 100 times more potent than morphine. The liquid’s street name: “BLOOD.” (All-caps is apparently the going style for the substance’s street name, but we’ll stick to “Blood” from this point forward because frankly, using BLOOD over and over again makes this article look like it was written by the Count from “Sesame Street”.)

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Scientists use gene editing to eliminate HIV DNA in live mice

A team of scientists have snipped away HIV DNA from the genome of live mice using a CRISPR system, and the rodents lived to (kinda) tell the tale. It’s still much too early to call the method a possible cure, but the fact that it worked on a living animal opens up a lot of possibilities. Will it work on other diseases, like cancer? Maybe, but that’s something scientists have to look into. These researchers headed by neurovirologist Kamel Khalili have been focusing on the use of the gene-editing technique to eliminate HIV for years. They successfully excised HIV DNA in live mice last year, but this round is a lot more thorough.

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