Two of Moderna’s mRNA-based HIV vaccines could start human trials this week, according to a new posting in the National Institutes of Health’s clinical trial registry. The Phase I study would test the vaccines’ safety, as well as collect basic data on whether they’re inducing any kind of immunity, but would still need to go through Phases II and III to see how effective they might be.
An experimental vaccine for covid-19 is showing some promising (though still very preliminary) results in people, according to its manufacturer. On Monday, biotech company Moderna announced its incomplete findings from a Phase 1 clinical trial of the vaccine candidate, called mRNA-1273. The trial found that the vaccine was overall tolerable and safe, and many of the participants also appeared to create antibodies to SARS-CoV-2, the coronavirus that causes covid-19. Continue reading An Experimental Vaccine for Covid-19 Shows Early Promise in Human Trial